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Updated 06/27/2012 09:15 AM

Native New York Filmmaker Nora Ephron Dies At 71

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Oscar-nominated filmmaker and author Nora Ephron has died.

A representative from Ephron's publishing company said the filmmaker died Tuesday from complications from leukemia.

She was known for the movies "When Harry Met Sally," "You've Got Mail," "Sleepless in Seattle" and "Julie and Julia."

She also wrote the books "Heartburn" and "Crazy Salad."

"I am very sad to learn of Nora's passing," said actor Billy Crystal, who worked with Ephron in "When Harry Met Sally. "She was a brilliant writer and humorist. Being her Harry to Meg's Sally will always have a special place in my heart. I was very lucky to get to say her words."

Mayor Michael Bloomberg releaased a statement saying, "Nora always loved a good New York story, and she could tell them like no one else. The books, movies and plays that she set in the world’s greatest city are classics that will be enjoyed for generations, but New York City will miss Nora very much."

Nora Ephron was 71 years old.